Ester-free thiol–ene dental restoratives—Part B: Composite development

Monosuccinate ester of melampomagnolide B

THE TITLE MONOSUCCINATE DERIVATIVE OF MELAMPOMAGNOLIDE B [SYSTEMATIC NAME: 4-(((1aR,7aS,10aS,10bS,E)-1a-methyl-8-meth-yl-ene-9-oxo-1a,2,3,6,7,7a,8,9,10a,10b-deca-hydro-oxireno[2',3':9,10]cyclo-deca-[1,2-b]furan-5-yl)meth-oxy)-4-oxo-butan-oic acid], C19H24O7, was obtained from the reaction of melampomagnolide B with succinic anhydride under nucleophilic addition reaction conditions. The mol-ecul...

The free energy of thiol ester hydrolysis.

Thiol esters, such as aeetyl coenzyme A, the principal biological carrier of activated acetyl groups, have generally been supposed to be “energy-rich” compounds; i.e. to have a free energy of hydrolysis at pH 7.0 in the range of -7000 to -14,000 calories per mole. The reported numerical values for the free energy of thiol ester hydrolysis have varied over a wide range (for recent estimates see ...

Low-shrinkage composite for dental application.

In modern research, development of monomers that reduce shrinkage of composite materials remains an ongoing quest and perennial challenge. The purpose of this study, therefore, was to analyze the shrinkage behaviour of an innovative composite material for dental restorations based on a monomer with a new chemical formulation, known as silorane. To this end, shrinkage stress development during c...

Beginnings of the dental composite revolution.

A Novel Antibacterial Dental Resin Composite

This study reports the synthesis and evaluation of a novel furanone-containing antibacterial resin composite. Compressive strength (CS) and S. mutans viability were used to evaluate the mechanical strength and antibacterial activity of the composites. With 5% to 30% addition of the furanone derivative, the composite showed no change in CS but a significant antibacterial activity with a 16% 68% ...